A native New Yorker, Sirota’s earliest compositional training began at the Juilliard School; he received his bachelor’s degree in piano and composition from the Oberlin Conservatory, where he studied with Joseph Wood and Richard Hoffman. A Thomas J. Watson Fellowship allowed him to study and concertize in Paris, where his principal teacher was Nadia Boulanger. Returning to America, Sirota earned a Ph.D. from Harvard University, studying with Earl Kim and Leon Kirchner.  

Before becoming Director of the Peabody Institute of the Johns Hopkins University in 1995, Sirota served as Chairman of the Department of Music and Performing Arts Professions at New York University and Director of Boston University's School of Music. From 2005-2012, he was the President of Manhattan School of Music, where he was also a member of the School’s composition faculty.  

Sirota divides his time between New York and his home in Searsmont, Maine, with his wife, Episcopal priest and organist Victoria Sirota. For the Sirotas, music is a family affair. They frequently collaborate on new works, with Victoria as librettist and performer, at times also working with their two children, Jonah and Nadia, both world-class violists. In his spare time, Sirota is an amateur painter and often depicts the landscape around Muzzy Ridge and Levenseller Mountain near his home in Maine.